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Proteintech
PIN1 Recombinant Rabbit Monoclonal Antibody (5N20)
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Product Details
81857-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5N20
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG DLGAFSRGQM QKPFEDASFA LRTGEMSGPV FTDSGIHIIL RTE
Target Information
PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 5.2.1.8; NIMA-interacting; parvulin PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein interacting with never in mitosis A1; Rotamase Pin1; UBL5; unnamed protein product
Gene Aliases: 0610025L01Rik; D9Bwg1161e; DOD; PIN1; UBL5
UniProt ID: (Human) Q13526, (Mouse) Q9QUR7
Entrez Gene ID: (Pig) 100512827, (Human) 5300, (Mouse) 23988, (Rat) 298696
peptidyl-prolyl cis-trans isomerase activity
motor activity
protein binding
beta-catenin binding
isomerase activity
cis-trans isomerase activity
mitogen-activated protein kinase kinase binding
GTPase activating protein binding
tau protein binding
phosphoserine binding
phosphothreonine binding
phosphoprotein binding
ubiquitin ligase activator activity
chaperone
protein peptidyl-prolyl isomerization
response to hypoxia
positive regulation of protein phosphorylation
protein targeting to mitochondrion
regulation of mitotic nuclear division
Rho protein signal transduction
regulation of gene expression
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
regulation of cytokinesis
negative regulation of protein catabolic process
positive regulation of transcription from RNA polymerase II promoter
microtubule polymerization
synapse organization
protein stabilization
negative regulation of SMAD protein import into nucleus
negative regulation of ERK1 and ERK2 cascade
cellular response to hypoxia
positive regulation of canonical Wnt signaling pathway
regulation of protein localization to nucleus
negative regulation of beta-amyloid formation
negative regulation of cell motility
cell cycle
positive regulation of protein dephosphorylation
regulation of cell proliferation
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of ubiquitin-protein transferase activity
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of cell growth involved in cardiac muscle cell development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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