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Proteintech
STX17 Recombinant Rabbit Monoclonal Antibody (4G3)
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Product Details
81899-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Mammalian cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4G3
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSEDEEKVKL RRLEPAIQKF IKIVIPTDLE RLRKHQINIE KYQRCGIWDK LHEEHINAGR TVQQLRSNIR EIEKLCLKVR KDDLVLLKRM IDPVKEEASA ATAEFLQLHL ESVEELKKQF NDEETLLQPP LTRSMTVGGA FHTTEAEASS QSLTQIYALP EIPQDQNAAE SWETLEADLI ELSQLVTDFS LLVNSQQEKI DSIADHVNSA AVNVEE
Target Information
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Syntaxin-17; unnamed protein product
Gene Aliases: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351; STX17
UniProt ID: (Human) P56962, (Rat) Q9Z158, (Mouse) Q9D0I4
Entrez Gene ID: (Human) 55014, (Rat) 252853, (Mouse) 67727
intracellular protein transport
exocytosis
ER to Golgi vesicle-mediated transport
vesicle fusion
autophagy
Golgi organization
vesicle-mediated transport
autophagosome membrane docking
protein localization to pre-autophagosomal structure
vesicle docking
autophagosome-lysosome fusion
endoplasmic reticulum-Golgi intermediate compartment organization
autophagosome maturation
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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