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Proteintech
NAGS Recombinant Rabbit Monoclonal Antibody (230279D3)
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Product Details
82963-1-RR
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
230279D3
Immunogen
NAGS fusion protein Ag16073
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MDMKPLVVLG LPAPTAPSGC LSFWEAKAQL AKSCKVLVDA LRHNAAAAVP FFGGGSVLRA AEPAPHASYG GIVSVETDLL QWCLESGSIP ILCPIGETAA RRSVLLDSLE VTASLAKALR PTKIIFLNNT GGLRDSSHKV LSNVNLPADL DLVCNAEWVS TKERQQMRLI VDVLSRLPHH SSAVITAAST LLTELFSNKG SGTLFKNAER MLRVRSLDKL DQGRLVDLVN ASFGKKLRDD YLASLRPRLH SIYVSEGYNA AAILTMEPVL GGTPYLDKFV VSSSRQGQGS GQMLWECLRR DLQTLFWRSR VTNPINPWYF KHSDGSFSNK QWIFFWFGLA DIRDSYELVN HAKGLPDSFH KPASDPGS
Target Information
NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amino acid acetyltransferase; Amino-acid acetyltransferase; amino-acid N-acetyltransferase; MGC133025; N-acetylglutamate synthase, mitochondrial; unnamed protein product
Gene Aliases: 1700120E20Rik; AGAS; ARGA; NAGS; RGD1565783
UniProt ID: (Human) Q8N159, (Mouse) Q8R4H7
Entrez Gene ID: (Human) 162417, (Rat) 303563, (Mouse) 217214
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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