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          • Primary Antibodies ›
          • HP1 beta Antibodies

          Proteintech

          CBX1 Recombinant Rabbit Monoclonal Antibody (240075H6)

          View all (15) HP1 beta antibodies

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          Cite CBX1 Recombinant Rabbit Monoclonal Antibody (240075H6)

          Additional Information:
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          • Antibody Testing Data (5)
          CBX1 Antibody in Immunocytochemistry (ICC/IF)
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          CBX1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          CBX1 Antibody (83248-4-RR) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CBX1 antibody (83248-4-RR, Clone: 240075H6) at dilution of 1:300 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG (H+L) (SA00013-2), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          CBX1 Antibody in Immunocytochemistry (ICC/IF)
          CBX1 Antibody in Immunocytochemistry (ICC/IF)
          CBX1 Antibody in Western Blot (WB)
          CBX1 Antibody in Flow Cytometry (Flow)
          CBX1 Antibody in Surface plasmon resonance (SPR)
          CBX1 Recombinant Rabbit Monoclonal Antibody (240075H6)

          Product Details

          83248-4-RR

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:5,000-1:50,000
          -

          Immunocytochemistry (ICC/IF)

          1:150-1:600
          -

          Flow Cytometry (Flow)

          0.25 µg/10^6 cells in a 100 µL suspension
          -

          ELISA (ELISA)

          Assay-dependent
          -

          Surface plasmon resonance (SPR)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Expression System

          CHO cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          240075H6

          Immunogen

          CBX1 fusion protein Ag34901
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: CPDLIAEFLQ SQKTAHETDK SEGGKRKADS DSEDKGEESK PKKKKEESEK PRGFAR

          Target Information

          This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CBX1; chromobox homolog 1; chromobox homolog 1 (HP1 beta homolog Drosophila ); Chromobox protein homolog 1; Heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; Heterochromatin protein p25; heterochromatin protein p25 beta; HGNC:1551; HP1 beta; HP1 beta homolog; HP1Hsbeta; M31; Modifier 1 protein; p25beta; unnamed protein product

          View more View less

          Gene Aliases: CBX; Cbx-rs2; CBX1; E430007M08Rik; HP1-BETA; HP1B; Hp1beta; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta

          View more View less

          UniProt ID: (Human) P83916, (Mouse) P83917

          View more View less

          Entrez Gene ID: (Human) 10951, (Mouse) 12412

          View more View less

          Function(s)
          chromatin binding protein binding enzyme binding identical protein binding histone methyltransferase binding protein homodimerization activity
          Process(es)
          cellular response to DNA damage stimulus heterochromatin assembly negative regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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