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          • Primary Antibodies ›
          • MED12L Antibodies

          Proteintech

          MED12L Recombinant Rabbit Monoclonal Antibody (240101C11)

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          Cite MED12L Recombinant Rabbit Monoclonal Antibody (240101C11)

          Additional Information:
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          • Antibody Testing Data (5)
          MED12L Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          MED12L Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          MED12L Antibody (83540-1-RR) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using MED12L antibody (83540-1-RR, Clone: 240101C11) at dilution of 1:300 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG (H+L) (SA00013-1), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          MED12L Antibody in Immunocytochemistry (ICC/IF)
          MED12L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MED12L Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MED12L Antibody in Flow Cytometry (Flow)
          MED12L Antibody in Flow Cytometry (Flow)
          MED12L Recombinant Rabbit Monoclonal Antibody (240101C11)

          Product Details

          83540-1-RR

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:150-1:600
          -

          Flow Cytometry (Flow)

          0.25 µg/10^6 cells in a 100 µL suspension
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          240101C11

          Immunogen

          MED12L fusion protein Ag34636
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: LSVTASTRPR SPVGENADEH YSKDHDVKME IFSPMPGESC ENANTSLGRR MSVNCEKLVK REKPRELIFP SNYDLLRHLQ

          Target Information

          MED12L, also named as KIAA1635, TNRC11L, TRALP and TRALPUSH, belongs to the Mediator complex subunit 12 family. MED12L may be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED12L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED12L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: mediator complex subunit 12 like; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; mediator of RNA polymerase II transcription, subunit 12 homolog-like; no opposite paired repeat protein; Thyroid hormone receptor-associated-like protein; TRAP230-like protein; Trinucleotide repeat-containing gene 11 protein-like; unnamed protein product

          View more View less

          Gene Aliases: KIAA1635; MED12L; NIZIDS; NOPAR; PRO0314; TNRC11L; TRALP; TRALPUSH

          View more View less

          UniProt ID: (Human) Q86YW9

          View more View less

          Entrez Gene ID: (Human) 116931

          View more View less

          Function(s)
          transcription cofactor activity transcription coactivator activity protein binding beta-catenin binding
          Process(es)
          regulation of transcription from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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