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Invitrogen
CD300a Monoclonal Antibody (MEM-260), PE
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FIGURE: 1 / 1
CD300a Antibody (A15778) in Flow
Cell reports. Medicine 2021 -
Figure 7 Functional investigation of differentially expressed genes in gammadelta[2] versus gammadelta[T2] cells (A) IL-9 was measured in supernatants harvested on day 15 from gammadelta[2] and gammadelta[T2] cells (values for individual donors are linked by a line; unpaired 2-tailed Student's t test). (B) IL-9 receptor expression was quantified on gammadelta[2] and gammadelta[T2] cells on day 15 using flow... View More
Product Details
A15778
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
MEM-260
Immunogen
HPB human lymphoid leukemia cell line.
Conjugate
Excitation/Emission Max
565/576 nm
View spectra
Form
Liquid
Purification
Size-exclusion chromatography
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
15mM sodium azide
Storage conditions
4°C, store in dark, DO NOT FREEZE!
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody reacts with an extracellular epitope of CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T cells and 15% of circulating B cells.
Target Information
The CMRF35 antigen (CMRF35A; MIM 606786), which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes. CMRF35H is recognized by the same antibody and is distinct from CMRF35 (Green et al., 1998 [PubMed 9701027]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD300 antigen-like family member A; CD300a; CD300a antigen; CLM-8; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H leukocyte immunoglobulin-like receptor; CMRF35HIRp60; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1/IRC2; IRC1a; IRC1b; IRC1c; IRp60; leukocyte membrane antigen; Mcipr1; NK inhibitory receptor; NKRL
Gene Aliases: CD300A; CLM-8; CMRF-35-H9; CMRF-35H; CMRF35-H; CMRF35-H9; CMRF35H; CMRF35H9; HSPC083; IGSF12; IRC1; IRC1/IRC2; IRC2; IRp60
UniProt ID: (Human) Q9UGN4
Entrez Gene ID: (Human) 11314
immune system process
cell adhesion
signal transduction
negative regulation of B cell proliferation
negative regulation of mast cell activation involved in immune response
negative regulation of MyD88-dependent toll-like receptor signaling pathway
intracellular signal transduction
negative regulation of mast cell degranulation
negative regulation of MAP kinase activity
regulation of innate immune response
negative regulation of fibroblast proliferation
regulation of T cell receptor signaling pathway
negative regulation of B cell receptor signaling pathway
negative regulation of NK T cell activation
negative regulation of phagocytosis, engulfment
negative regulation of neutrophil activation
negative regulation of eosinophil activation
negative regulation of eosinophil migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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