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Proteintech
A2BP1 Polyclonal Antibody
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Product Details
22647-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A2BP1 Fusion Protein Ag18527 (1-128 aa encoded by BC113691)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This is a rabbit polyclonal antibody raised against the N terminus of human A2BP1.
Immunogen sequence: MLASQGVLL HPYGVPMIVP AAPYLPGLIQ GNQEAAAAPD TMAQPYASAQ FAPPQNGIPA EYTAPHPHPA PEYTGQTTVP EHTLNLYPPA QTHSEQSPAD TSAQTVSGTA TQTDDAAPTD GQPQTQPSE (1-128 aa encoded by BC113691 )
Target Information
Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A FOX-1; ataxin 2 binding protein 1; ataxin 2-binding protein 1; Ataxin-2-binding protein 1; Fox-1 homolog A; fox-1-like RNA-binding protein 1; hexaribonucleotide binding protein 1; hexaribonucleotide binding protein 1 isoform alpha; hexaribonucleotide binding protein 1 isoform beta; Hexaribonucleotide-binding protein 1; RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog (C. elegans) 1
Gene Aliases: 2BP1; A2BP; A2BP1; FOX-1; FOX1; HRNBP1; MNCb-3035; RBFOX1
UniProt ID: (Human) Q9NWB1, (Mouse) Q9JJ43
Entrez Gene ID: (Human) 54715, (Mouse) 268859
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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