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Bethyl Laboratories
G6PD Polyclonal Antibody
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FIGURE: 1 / 2
G6PD Antibody (A300-404A-T) in WB
Detection of human G6PD by western blot. Samples: Whole cell lysate (5 µg) from HeLa, HEK293T, K-562, Jurkat, and Hep-G2 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-G6PD antibody (Product # A300-404A lot 5) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A300-404A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 50 and 100 of human Glucose-6-Phosphate Dehydrogenase.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; G6PD; Glucose-6-phosphate 1-dehydrogenase; Glucose-6-phosphate 1-dehydrogenase X; glucose-6-phosphate dehydrogenase variant A- (EC 1.1.1.49); unnamed protein product
Gene Aliases: CNSHA1; G28A; G6PD; G6pd-1; G6PD1; G6pdx; Gpdx
UniProt ID: (Human) P11413, (Mouse) Q00612
Entrez Gene ID: (Human) 2539, (Mouse) 14381
glucose metabolic process
pentose-phosphate shunt
lipid metabolic process
cholesterol biosynthetic process
NADP metabolic process
NADPH regeneration
glutathione metabolic process
pentose-phosphate shunt, oxidative branch
response to iron(III) ion
pentose biosynthetic process
substantia nigra development
response to food
cellular response to oxidative stress
erythrocyte maturation
regulation of neuron apoptotic process
response to ethanol
ribose phosphate biosynthetic process
glucose 6-phosphate metabolic process
negative regulation of cell growth involved in cardiac muscle cell development
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
negative regulation of reactive oxygen species metabolic process
cytokine production
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure
vasodilation by angiotensin involved in regulation of systemic arterial blood pressure
carbohydrate metabolic process
NADP biosynthetic process
response to oxidative stress
negative regulation of protein glutathionylation
interleukin-10 production
interleukin-12 production
regulation of multicellular organism growth
erythrocyte development
oxidation-reduction process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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