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Bethyl Laboratories

TPR Polyclonal Antibody

View all (12) TPR antibodies

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TPR Polyclonal Antibody

Product Details

A300-825A-T

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
-

Immunoprecipitation (IP)

2-5 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 600 and 650 of Human Translocated Promoter Region Protein.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.20 mg/mL

Amount

2 µg

Purification

Antigen affinity chromatography

Storage buffer

TBS, pH 7.0 to 8.0, with 0.1% BSA

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Steroidogenic factor-1 (SF-1) regulates multiple genes involved in the adrenal and gonadal development and in the biosynthesis of a variety of hormones, including adrenal and gonadal steroids, anti-Mullerian hormone (AMH), and gonadotropins. SF-1 belongs to the fushi tarazu factor-1 (FTZ-F1) subfamily of orphan nuclear receptors. In the adult ovary, SF-1 localizes to theca/interstitial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Megator; NPC-associated intranuclear protein; nuclear pore complex-associated protein TPR; Nucleoprotein TPR; Tpr; translocated promoter region (to activated MET oncogene); Translocated promoter region protein; tumor potentiating region; unnamed protein product

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Gene Aliases: MRT79; TPR

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UniProt ID: (Human) P12270

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Entrez Gene ID: (Human) 7175

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Function(s)
chromatin binding RNA binding mRNA binding protein binding tubulin binding structural constituent of nuclear pore heat shock protein binding protein homodimerization activity protein anchor mitogen-activated protein kinase binding dynein complex binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter RNA import into nucleus RNA export from nucleus mRNA export from nucleus protein import into nucleus protein export from nucleus intracellular protein transport nucleocytoplasmic transport nuclear pore organization mitotic spindle assembly checkpoint regulation of mRNA export from nucleus regulation of mitotic sister chromatid separation protein transport positive regulation of heterochromatin assembly regulation of protein stability mRNA export from nucleus in response to heat stress regulation of protein localization cellular response to heat cellular response to interferon-alpha regulation of protein import into nucleus positive regulation of protein import into nucleus nuclear matrix organization negative regulation of translational initiation positive regulation of nucleocytoplasmic transport regulation of protein export from nucleus positive regulation of protein export from nucleus negative regulation of RNA export from nucleus mRNA transport nuclear export nuclear pore complex assembly cell division response to epidermal growth factor positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of intracellular protein transport regulation of mitotic spindle assembly
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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