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Bethyl Laboratories
G9A/EHMT2 Polyclonal Antibody
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Product Details
A300-933A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1160 and the C-terminus (residue 1210) of human G9A (Euchromatic Histone-Lysine N-Methyltransferase 2).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Target Information
A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ankyrin repeat-containing protein; DKFZp686H08213; Euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G9A histone methyltransferase; H3 ly; H3-K9-Histone-Methyl-Transferase; H3-K9-HMTase 3; Histone H3-K9 methyltransferase 3; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; HLA-B associated transcript 8; HLA-B-associated transcript 8; Lysine N-methyltransferase 1C; NG36/G9a; Protein G9a; unnamed protein product
Gene Aliases: BAT8; C6orf30; EHMT2; G9A; GAT8; KMT1C; NG36
UniProt ID: (Human) Q96KQ7
Entrez Gene ID: (Human) 10919
RNA polymerase II regulatory region sequence-specific DNA binding
transcription corepressor binding
p53 binding
protein binding
methyltransferase activity
zinc ion binding
protein-lysine N-methyltransferase activity
transferase activity
histone methyltransferase activity
metal ion binding
histone methyltransferase activity (H3-K9 specific)
histone methyltransferase activity (H3-K27 specific)
C2H2 zinc finger domain binding
histone H3K56 methyltransferase activity
histone H3 methyltransferase activity
histone H3K9me2 methyltransferase activity
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
regulation of DNA replication
chromatin organization
methylation-dependent chromatin silencing
regulation of transcription from RNA polymerase II promoter
synaptonemal complex assembly
spermatid development
cellular response to starvation
fertilization
peptidyl-lysine dimethylation
methylation
organ growth
phenotypic switching
regulation of gene expression, epigenetic
hypermethylation of CpG island
behavioral response to cocaine
oocyte development
neuron fate specification
cellular response to cocaine
negative regulation of autophagosome assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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