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Bethyl Laboratories
PTPN12 Polyclonal Antibody
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Product Details
A301-301A-T
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 710 and 760 of Human protein tyrosine phosphatase, non-receptor type 12.
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Amount
2 µg
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
PTP PEST is an 88 kDa cytosolic protein tyrosine phosphatase which is ubiquitiously expressed in mammalian tissues. PTP PEST exhibits a high specific activity when assayed in vitro with artificial tyrosine-phosphorylated substrates. PTP PEST is subject to regulation via phosphorylation of ser 39 and is catalyzed by both protein kinase C and protein kinase A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: pest; Protein-tyrosine phosphatase G1; PTP-PEST; PTPG1; tcag7.1075; tumor suppressor; tumor suppressor; pTP; Tyrosine-protein phosphatase non-receptor type 12; unnamed protein product
Gene Aliases: PTP-PEST; PTPG1; PTPN12
UniProt ID: (Human) Q05209
Entrez Gene ID: (Human) 5782
protein dephosphorylation
peptidyl-tyrosine dephosphorylation
regulation of epidermal growth factor receptor signaling pathway
tissue regeneration
cellular response to epidermal growth factor stimulus
negative regulation of ERBB signaling pathway
negative regulation of platelet-derived growth factor receptor-beta signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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