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Bethyl Laboratories
Ribosomal Protein L23/RPL23 Polyclonal Antibody
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FIGURE: 1 / 2
Ribosomal Protein L23/RPL23 Antibody (A305-008A) in WB
Detection of human and mouse Ribosomal Protein L23 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Ribosomal Protein L23 antibody (Product # A305-008A) (lot A305-008A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A305-008A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 50 to 100 of Human 60S ribosomal protein L23.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, Bovine, Pig and Orangutan
Target Information
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L17; 60S ribosomal protein L23; Large ribosomal subunit protein uL14; MGC111167; MGC117346; MGC72008; ribosomal protein L17
Gene Aliases: 2810009A01Rik; L23; rpL17; RPL23; uL14
UniProt ID: (Human) P62829, (Mouse) P62830
Entrez Gene ID: (Human) 9349, (Mouse) 65019
negative regulation of transcription from RNA polymerase II promoter
cytoplasmic translation
translation
ribosomal protein import into nucleus
positive regulation of cell proliferation
positive regulation of gene expression
protein-DNA complex disassembly
protein stabilization
G1 to G0 transition
cellular response to actinomycin D
positive regulation of signal transduction by p53 class mediator
regulation of G1 to G0 transition
negative regulation of ubiquitin protein ligase activity
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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