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          • Primary Antibodies ›
          • Nesprin 2 Antibodies

          Bethyl Laboratories

          SYNE2/Nesprin 2 Polyclonal Antibody

          View all (8) Nesprin 2 antibodies

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          Cite SYNE2/Nesprin 2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          SYNE2/Nesprin 2 Antibody in Immunoprecipitation (IP)
          Group 53 Created with Sketch.
          SYNE2/Nesprin 2 Antibody in Immunoprecipitation (IP)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SYNE2/Nesprin 2 Antibody (A305-392A-T) in IP

          Detection of human SYNE2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SYNE2 antibody (Product # A305-392A) (lot 1) used for IP at 6 µg per reaction. SYNE2 was also immunoprecipitated by rabbit anti-SYNE2 antibody A305-393A. For blotting immunoprec... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SYNE2/Nesprin 2 Antibody in Immunoprecipitation (IP)
          SYNE2/Nesprin 2 Polyclonal Antibody

          Product Details

          A305-392A-T

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          2-10 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1075 to 1125 of Human Nesprin-2.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          phosphate/tris citrate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Target Information

          The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: actin-binding protein; actin-binding protein associated with nuclear envelope; cytoskeletal protein; KASH domain-containing protein 2; KASH2; MGC96690; nesprin 2; Nesprin-2; nesprin-2 spectrin repeats 3-54; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element protein; polytrophin; Protein NUANCE; short isoform; spectrin repeat containing, nuclear envelope 2; Synaptic nuclear envelope protein 2; synaptic nuclei expressed gene 2; Syne-2; unnamed protein product

          View more View less

          Gene Aliases: EDMD5; KASH2; KIAA1011; Nesp2; Nesprin-2; NUA; NUANCE; SYNE-2; SYNE2; TROPH

          View more View less

          UniProt ID: (Human) Q8WXH0

          View more View less

          Entrez Gene ID: (Human) 23224

          View more View less

          Function(s)
          actin binding protein binding cytoskeleton-nuclear membrane anchor activity
          Process(es)
          nuclear migration nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration positive regulation of cell migration nuclear migration along microfilament centrosome localization regulation of cilium assembly
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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