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The predicted MW of this protein is 35 kDa. 27319-1-AP recognizes a 37-40 kDa band due to phosphorylation.
Immunogen sequence: MAAGVPCAL VTSCSSVFSG DQLVQHILGT EDLIVEVTSN DAVRFYPWTI DNKYYSADIN LCVVPNKFLV TAEIAESVQA FVVYFDSTQK SGLDSVSSWL PLAKAWLPEV MILVCDRVSE DGINRQKAQE WCIKHGFELV ELSPEELPEE DDDFPESTGV KRIVQALNAN VWSNVVMKND RNQGFSLLNS LTGTNHSIGS ADPCHPEQPH LPAADSTESL SDHRGGASNT TDAQVDSIVD PMLDLDIQEL ASLTTGGGDV ENFERLFSKL KEMKDKAATL PHEQRKVHAE KVAKAFWMAI GGDRDEIEGL SSDEEH (1-315 aa encoded by B C058886)
The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene.
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Protein Aliases: Alpha- and gamma-adaptin-binding protein p34
Gene Aliases: 2310007F21Rik; AAGAB; KPPP1; p34; PPKP1; PPKP1A
UniProt ID: (Human) Q6PD74, (Mouse) Q8R2R3
Entrez Gene ID: (Human) 79719, (Mouse) 66939
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