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Invitrogen
ABAT Polyclonal Antibody
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Product Details
PA5-27405
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ABAT. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: SK-N-SH, mouse brain, rat liver.
Predicted reactivity: Mouse (93%), Rat (93%), Xenopus laevis (82%), Pig (95%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; 4-aminobutyrate transaminase; beta-AlaAT I; beta-alanine oxoglutarate aminotransferase; FLJ17813; FLJ30272; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; Gamma-amino-N-butyrate transaminase; hCG1984265; L AIBAT; L-AIBAT
Gene Aliases: 9630038C02Rik; ABAT; AI255750; beta-AlaAT; ENSMUSG00000051226; GABA-AT; Gabaat; GABAT; Gm9851; I54; Laibat; NPD009; X61497
UniProt ID: (Human) P80404, (Rat) P50554, (Mouse) P61922
Entrez Gene ID: (Human) 18, (Rat) 81632, (Mouse) 268860
4-aminobutyrate transaminase activity
pyridoxal phosphate binding
succinate-semialdehyde dehydrogenase binding
protein homodimerization activity
metal ion binding
(S)-3-amino-2-methylpropionate transaminase activity
iron-sulfur cluster binding
catalytic activity
transaminase activity
transferase activity
transaminase
response to hypoxia
aging
copulation
locomotory behavior
gamma-aminobutyric acid biosynthetic process
gamma-aminobutyric acid catabolic process
response to iron ion
negative regulation of gamma-aminobutyric acid secretion
cerebellum development
positive regulation of heat generation
positive regulation of insulin secretion
negative regulation of dopamine secretion
response to nicotine
exploration behavior
neurotransmitter catabolic process
response to drug
response to ethanol
negative regulation of blood pressure
positive regulation of dopamine metabolic process
behavioral response to cocaine
positive regulation of uterine smooth muscle contraction
negative regulation of platelet aggregation
positive regulation of inhibitory postsynaptic potential
positive regulation of prolactin secretion
positive regulation of aspartate secretion
response to cocaine
gamma-aminobutyric acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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