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Invitrogen
ABCA3 Polyclonal Antibody
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Product Details
PA5-118968
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein ATP Binding Cassette Transporter A3. The antigen corresponds to amino acid range 1358-1635 of the target protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC transporter 3; ABC-C transporter; ATP-binding cassette 3; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette, sub-family A (ABC1), member 3; Phospholipid-transporting ATPase ABCA3; Xenobiotic-transporting ATPase ABCA3
Gene Aliases: ABC-C; ABC3; ABCA3; EST111653; LBM180; SMDP3
UniProt ID: (Human) Q99758, (Rat) A0A0G2K1Q8
Entrez Gene ID: (Human) 21, (Rat) 302973
nucleotide binding
lipid transporter activity
ATP binding
xenobiotic-transporting ATPase activity
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
phosphatidylcholine transfer activity
ATPase-coupled intramembrane lipid transporter activity
phosphatidylcholine flippase activity
ABC-type transporter activity
molecular_function
transporter activity
ATP-binding cassette (ABC) transporter
primary active transporter
transporter
drug transmembrane transport
lipid transport
response to xenobiotic stimulus
positive regulation of cholesterol efflux
phospholipid transport
lung development
regulation of lipid transport
positive regulation of protein homooligomerization
lipid translocation
xenobiotic transport
surfactant homeostasis
phosphatidylcholine metabolic process
phosphatidylglycerol metabolic process
drug export
regulation of lipid biosynthetic process
response to glucocorticoid
transmembrane transport
phospholipid homeostasis
organelle assembly
intermembrane lipid transfer
regulation of phosphatidylcholine metabolic process
positive regulation of phospholipid efflux
positive regulation of phospholipid transport
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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