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| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide derived from human ABCB6, amino acids 401-520. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.09% sodium azide |
Storage conditions |
-20°C |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); EST45597; FLJ22414; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter
Gene Aliases: 1200005B17Rik; ABC; ABC14; ABCB6; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; UMAT
UniProt ID: (Human) Q9NP58, (Rat) O70595, (Mouse) Q9DC29
Entrez Gene ID: (Human) 10058, (Rat) 140669, (Mouse) 74104
Molecular Function:
ATP-binding cassette (ABC) transporter
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