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ABCB6 Polyclonal Antibody
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Product Details
BS-1224R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ABCB6, amino acids 401-520.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC; ABC-type heme transporter ABCB6; ATP binding cassette subfamily B member 6 (Langereis blood group); ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 6; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); EST45597; FLJ22414; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; unnamed protein product
Gene Aliases: 1200005B17Rik; ABC; ABCB6; LAN; MTABC3; PRP; UMAT
UniProt ID: (Human) Q9NP58, (Rat) O70595, (Mouse) Q9DC29
Entrez Gene ID: (Human) 10058, (Rat) 140669, (Mouse) 74104
nucleotide binding
ATP binding
heme transporter activity
heme-transporting ATPase activity
efflux transmembrane transporter activity
ATPase activity
heme binding
tetrapyrrole binding
ABC-type transporter activity
ATPase activity, coupled to transmembrane movement of substances
ATP-binding cassette (ABC) transporter
porphyrin-containing compound metabolic process
porphyrin-containing compound biosynthetic process
heme B biosynthetic process
cellular copper ion homeostasis
cellular iron ion homeostasis
brain development
heme transport
tetrapyrrole metabolic process
iron ion transmembrane transport
heme transmembrane transport
heme metabolic process
skin development
transmembrane transport
cellular detoxification of cadmium ion
melanosome assembly
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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