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Invitrogen
ABCB8 Polyclonal Antibody
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Product Details
PA5-120826
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein (or fragment)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Amount
37 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: MCF7, Jurkat, HepG2, HeLa, Mouse heart, Mouse skin, Mouse kidney, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein.
Immunogen sequence: GFEVLKDFTL TLPPGKIVAL VGQSGGGKTT VASLLERFYD PTAGVVMLDG RDLRTLDPSW LRGQVVGFIS QEPVLFGTTI MENIRFGKLE ASDEEVYTAA REANAHEFIT SFPEGYNTVV GERGTTLSGG QKQRLAIARA LIKQPTVLIL DEATSALDAE SERVVQEALD RASAGRTVLV IAHRLSTVRG AHCIVVMADG RVWEAGTHEE LLKKGGLYAE LIRRQALDAP RTAAPPPKKP EGPRSHQHKS
Target Information
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABC transporter 8; ABCB8; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 8; ATP-binding cassette, sub-family B, member 8; M-ABC1; mitochondrial ABC protein; Mitochondrial ATP-binding cassette 1; Mitochondrial potassium channel ATP-binding subunit; Mitochondrial sulfonylurea-receptor; MITOSUR; unnamed protein product
Gene Aliases: 4833412N02Rik; AA409895; ABCB8; EST328128; M-ABC1; MABC1; MITOSUR
UniProt ID: (Human) Q9NUT2, (Mouse) Q9CXJ4, (Rat) Q5RKI8
Entrez Gene ID: (Human) 11194, (Mouse) 74610, (Rat) 362302
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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