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Proteintech
ABCC10 Polyclonal Antibody
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Product Details
30697-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCC10 fusion protein Ag33719
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-binding cassette sub-family C member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; Multidrug resistance-associated protein 7; transporter
Gene Aliases: ABCC10; EST182763; mFLJ00002; MRP7; SIMRP7
UniProt ID: (Human) Q5T3U5, (Mouse) Q8R4P9
Entrez Gene ID: (Human) 89845, (Mouse) 224814
nucleotide binding
ATP binding
xenobiotic-transporting ATPase activity
glutathione S-conjugate-exporting ATPase activity
ATPase activity
xenobiotic transporter activity
anion transmembrane-transporting ATPase activity
ABC-type transporter activity
ATPase activity, coupled to transmembrane movement of substances
ATP-binding cassette (ABC) transporter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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