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Proteintech
ABCC6 Polyclonal Antibody
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Product Details
27848-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCC6 Fusion Protein Ag18640 (1219-1503 aa encoded by BC131732)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
27848-1-AP detects two isoforms of ABCC6 protein around 165 kDa and 96 kDa in SDS-PAGE.
Immunogen sequence: VVRNWTDLE NSIVSVERMQ DYAWTPKEAP WRLPTCAAQP PWPQGGQIEF RDFGLRYRPE LPLAVQGVSF KIHAGEKVGI VGRTGAGKSS LASGLLRLQE AAEGGIWIDG VPIAHVGLHT LRSRISIIPQ DPILFPGSLR MNLDLLQEHS DEAIWAALET VQLKALVASL PGQLQYKCAD RGEDLSVGQK QLLCLARALL RKTQILILDE ATAAVDPGTE LQMQAMLGSW FAQCTVLLIA HRLRSVMDCA RVLVMDKGQV AESGSPAQLL AQKGLFYRLA QESGLV (1219-1503 aa encoded by BC131732)
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; MOAT-E; Multi-specific organic anion transporter E; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6
Gene Aliases: ABC34; Abcc1b; ABCC6; ARA; DCC; dyscalc; Dyscalc1; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
UniProt ID: (Human) O95255, (Mouse) Q9R1S7
Entrez Gene ID: (Human) 368, (Mouse) 27421
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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