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Proteintech
ABCC6 Polyclonal Antibody
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Product Details
27848-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCC6 Fusion Protein Ag18640 (1219-1503 aa encoded by BC131732)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Amount
49.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
27848-1-AP detects two isoforms of ABCC6 protein around 165 kDa and 96 kDa in SDS-PAGE.
Immunogen sequence: VVRNWTDLE NSIVSVERMQ DYAWTPKEAP WRLPTCAAQP PWPQGGQIEF RDFGLRYRPE LPLAVQGVSF KIHAGEKVGI VGRTGAGKSS LASGLLRLQE AAEGGIWIDG VPIAHVGLHT LRSRISIIPQ DPILFPGSLR MNLDLLQEHS DEAIWAALET VQLKALVASL PGQLQYKCAD RGEDLSVGQK QLLCLARALL RKTQILILDE ATAAVDPGTE LQMQAMLGSW FAQCTVLLIA HRLRSVMDCA RVLVMDKGQV AESGSPAQLL AQKGLFYRLA QESGLV (1219-1503 aa encoded by BC131732)
Target Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; ATP-binding cassette, sub-family C, member 6; MOAT-E; Multi-specific organic anion transporter E; Multidrug resistance-associated protein 6; multidrug resistance-associated protein-6; similar to multidrug resistance protein MRP1; unnamed protein product
Gene Aliases: ABC34; Abcc1b; ABCC6; ARA; DCC; dyscalc; Dyscalc1; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7
UniProt ID: (Human) O95255, (Mouse) Q9R1S7
Entrez Gene ID: (Human) 368, (Mouse) 27421
nucleotide binding
ATP binding
glutathione S-conjugate-exporting ATPase activity
ATPase activity
transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
anion transmembrane-transporting ATPase activity
ABC-type transporter activity
ATP-binding cassette (ABC) transporter
visual perception
response to xenobiotic stimulus
gene expression
ATP transport
inorganic diphosphate transport
cellular phosphate ion homeostasis
response to magnesium ion
ATP metabolic process
carboxylic acid transport
phosphate ion homeostasis
calcium ion homeostasis
transmembrane transport
leukotriene transport
anion transmembrane transport
inhibition of non-skeletal tissue mineralization
response to sodium phosphate
transport
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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