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          • Primary Antibodies ›
          • MRP6 Antibodies

          Osenses

          ABCC6 Polyclonal Antibody

          2 References
          View all (13) MRP6 antibodies

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          Cite ABCC6 Polyclonal Antibody

          Additional Information:
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          ABCC6 Polyclonal Antibody

          Product Details

          OSA00223W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 850-950 of human ABCC6 conjugated to an immunogenic carrier protein was used as the antigen
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: ABCC6.

          Target Information

          The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; MOAT-E; Multi-specific organic anion transporter E; Multidrug resistance-associated protein 6; similar to multidrug resistance protein MRP1; unnamed protein product

          View more View less

          Gene Aliases: ABC34; ABCC6; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7

          View more View less

          UniProt ID: (Human) O95255

          View more View less

          Entrez Gene ID: (Human) 368

          View more View less

          Function(s)
          nucleotide binding ATP binding glutathione S-conjugate-exporting ATPase activity ATPase activity transmembrane transporter activity ATPase activity, coupled to transmembrane movement of substances anion transmembrane-transporting ATPase activity ABC-type transporter activity
          Process(es)
          visual perception response to xenobiotic stimulus gene expression ATP transport inorganic diphosphate transport cellular phosphate ion homeostasis response to magnesium ion ATP metabolic process carboxylic acid transport phosphate ion homeostasis calcium ion homeostasis transmembrane transport leukotriene transport anion transmembrane transport inhibition of non-skeletal tissue mineralization response to sodium phosphate
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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