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Invitrogen
ABCD1 Polyclonal Antibody
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Product Details
PA5-67620
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human ABCD1.
Conjugate
Form
Liquid
Concentration
1.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Predicted to react with Mouse samples.
Target Information
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1; ATP-binding cassette, sub-family D, member 1; X-linked adrenoleukodystrophy (ALD) gene homolog
Gene Aliases: ABC42; ABCD1; ALD; Aldgh; ALDP; AMN
UniProt ID: (Human) P33897, (Mouse) P48410
Entrez Gene ID: (Human) 215, (Mouse) 11666
transporter activity
long-chain fatty acid transporter activity
peroxisomal fatty-acyl-CoA transporter activity
protein binding
ATP binding
ATPase activity
enzyme binding
ATPase activity, coupled to transmembrane movement of substances
identical protein binding
protein homodimerization activity
nucleotide binding
ATP-binding cassette (ABC) transporter
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
peroxisomal membrane transport
fatty acid beta-oxidation using acyl-CoA oxidase
alpha-linolenic acid metabolic process
long-chain fatty acid catabolic process
very long-chain fatty acid catabolic process
linoleic acid metabolic process
transmembrane transport
transport
fatty-acyl-CoA transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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