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Proteintech
ABCD2 Polyclonal Antibody
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Product Details
18179-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCD2 Fusion Protein Ag12872 (371-740 aa encoded by BC104901)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ADGEDGQKQ VMVSERTEAF TTARNLLASG ADAIERIMSS YKEVTELAGY TARVYNMFWV FDEVKRGIYK RTAVIQESES HSKNGAKVEL PLSDTLAIKG KVIDVDHGII CENVPIITPA GEVVASRLNF KVEEGMHLLI TGPNGCGKSS LFRILSGLWP VYEGVLYKPP PQHMFYIPQR PYMSLGSLRD QVIYPDSVDD MHDKGYTDQD LERILHNVHL YHIVQREGGW DAVMDWKDVL SGGEKQRMGM ARMFYHKPKY ALLDECTSAV SIDVEGKIFQ AAKGAGISLL SITHRPSLWK YHTHLLQFDG EGGWRFEQLD TAIRLTLSEE KQKLESQLAG IPKMQQRLNE LCKILGEDSV LKTIKNEDET S (371-740 aa encoded by BC104901)
Target Information
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenoleukodystrophy related; Adrenoleukodystrophy-like 1; Adrenoleukodystrophy-related protein; ATP-binding cassette sub-family D member 2; ATP-binding cassette, sub-family D (ALD), member 2; hALDR; unnamed protein product
Gene Aliases: ABC39; ABCD2; ALD1; ALDL1; ALDR; ALDRP; hALDR
UniProt ID: (Human) Q9UBJ2, (Mouse) Q61285, (Rat) Q9QY44
Entrez Gene ID: (Human) 225, (Mouse) 26874, (Rat) 84356
nucleotide binding
long-chain fatty acid transporter activity
protein binding
ATP binding
organophosphate ester transmembrane transporter activity
nucleobase-containing compound transmembrane transporter activity
hydrolase activity
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
amide transmembrane transporter activity
protein heterodimerization activity
acyl-CoA hydrolase activity
ABC-type transporter activity
sulfur compound transmembrane transporter activity
ATP-binding cassette (ABC) transporter
very long-chain fatty acid metabolic process
fatty acid biosynthetic process
fatty acid beta-oxidation
unsaturated fatty acid biosynthetic process
peroxisome organization
response to bacterium
organophosphate ester transport
peroxisomal long-chain fatty acid import
nucleobase-containing compound transport
regulation of fatty acid metabolic process
positive regulation of fatty acid beta-oxidation
alpha-linolenic acid metabolic process
long-chain fatty acid biosynthetic process
very long-chain fatty acid catabolic process
amide transport
myelin maintenance
linoleic acid metabolic process
transmembrane transport
negative regulation of cytokine production involved in inflammatory response
fatty acid derivative biosynthetic process
negative regulation of reactive oxygen species biosynthetic process
neuron projection maintenance
positive regulation of unsaturated fatty acid biosynthetic process
transport
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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