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Invitrogen
ABCD2 Polyclonal Antibody
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FIGURE: 1 / 8
ABCD2 Antibody (PA5-118971) in IHC (P)
Immunohistochemistry (Paraffin) analysis of ABCD2 in mouse cardiac muscle tissue using ABCD2 Polyclonal Antibody (Product # PA5-118971) (20 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Rabbit IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-118971
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein ATP Binding Cassette Transporter D2. The antigen corresponds to amino acid range 501-695 of the target protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adrenoleukodystrophy related; adrenoleukodystrophy-like 1; adrenoleukodystrophy-related protein; ALDR; ATP-binding cassette, sub-family D (ALD), member 2; unnamed protein product
Gene Aliases: ABC39; ALDL1; ALDR; ALDRP; hALDR
UniProt ID: (Human) Q9UBJ2, (Mouse) Q61285
Entrez Gene ID: (Human) 225, (Mouse) 26874
long-chain fatty acid transporter activity
protein binding
ATP binding
ATPase activity
ATPase activity, coupled to transmembrane movement of substances
protein homodimerization activity
protein heterodimerization activity
acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
ABC-type transporter activity
very long-chain fatty acid metabolic process
fatty acid biosynthetic process
fatty acid beta-oxidation
peroxisome organization
peroxisomal long-chain fatty acid import
regulation of fatty acid metabolic process
positive regulation of fatty acid beta-oxidation
very long-chain fatty acid catabolic process
myelin maintenance
positive regulation of lipid metabolic process
transmembrane transport
negative regulation of cytokine production involved in inflammatory response
negative regulation of reactive oxygen species biosynthetic process
neuron projection maintenance
positive regulation of unsaturated fatty acid biosynthetic process
response to bacterium
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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