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Invitrogen
ABHD12 Polyclonal Antibody
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Product Details
PA5-101394
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ABHD12, corresponding to a region within C-terminal amino acids.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ABHD12.
Target Information
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol, the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC, resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-arachidonoylglycerol hydrolase; 2-arachidonoylglycerol hydrolase ABHD12; Abhydrolase domain-containing protein 12; DKFZP434P106; hABHD12; Lysophosphatidylserine lipase ABHD12; Monoacylglycerol lipase ABHD12; Oxidized phosphatidylserine lipase ABHD12
Gene Aliases: 1500011G07Rik; 6330583M11Rik; ABHD12; ABHD12A; AI431047; AW547313; BEM46L2; C20orf22; dJ965G21.2; PHARC
UniProt ID: (Human) Q8N2K0, (Mouse) A2ANB4, (Rat) Q6AYT7
Entrez Gene ID: (Human) 26090, (Mouse) 76192, (Rat) 499913
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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