Recommended positive controls: PC-3, NIH-3T3, BCL-1, Raw264.7, C2C12.
Predicted reactivity: Mouse (98%), Rat (96%), Chicken (85%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Abelson interactor 1; Abi-1; Abl interactor 1; Abl-binding protein 4; abl-interactor 1; Abl-interactor protein 1 long; AblBP4; Ablphilin-1; e3B1; EL2; eps8 binding protein; Eps8 SH3 domain-binding protein; Eps8-binding protein; HS3; interactor protein AblBP4; nap1 binding protein; Nap1-binding protein; Nap1BP; spectrin SH3 domain binding protein 1; Spectrin SH3 domain-binding protein 1; SPH3; SPTA
Gene Aliases: ABI-1; ABI1; ABLBP4; E3B1; NAP1; NAP1BP; SSH3BP; SSH3BP1