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Bioss
ABI2 Polyclonal Antibody
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Product Details
BS-5984R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ABI2, amino acids 421-513.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Abelson interactor 2; Abi-2; Abi-2b; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1; thyroid hormone responsive protein; unnamed protein product
Gene Aliases: 8430425M24Rik; ABI-2; ABI2; ABI2B; AblBP3; AI839867; AIP-1; AIP1; argBP1; ARGBPIA; argBPIB; C130078H13; SSH3BP2
UniProt ID: (Human) Q9NYB9, (Mouse) P62484
Entrez Gene ID: (Human) 10152, (Mouse) 329165, (Rat) 286928
mitophagy
neuron migration
cytoskeleton organization
nervous system development
actin polymerization or depolymerization
positive regulation of lamellipodium assembly
cell migration
Rac protein signal transduction
peptidyl-tyrosine phosphorylation
zonula adherens assembly
cell projection morphogenesis
regulation of dendritic spine morphogenesis
lens fiber cell morphogenesis
positive regulation of Arp2/3 complex-mediated actin nucleation
movement of cell or subcellular component
learning or memory
dendrite development
camera-type eye development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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