Immunogen sequence: QGSTVWHPDC KQSTKTEEKL RLPNIRRSSS DFFYSKSLIR RTGRSPSLQP TRTSS
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 72%.
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: ABLIM; abLIM-1; Actin-binding double zinc finger protein; actin-binding double-zinc-finger protein; Actin-binding LIM protein 1; Actin-binding LIM protein family member 1; LIMAB1; LIMATIN
Gene Aliases: ABLIM; abLIM-1; ABLIM1; KIAA0059; LIMAB1; LIMATIN
UniProt ID: (Human) O14639
Entrez Gene ID: (Human) 3983