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Immunogen sequence: TFHYYDADD PVHYPRALCL FEMPTGVPLR RHFNSNFKGG FNFYAGLKGQ VLVLRTTSTV YNYDYIWDFI FYPNGVMEAK MHATGYVHAT FYTPEGLRHG TRLHTHLIGN IHTHLVHYRV DLDVAGTKNS FQTLQMKLEN ITNPWSPRHR VVQPTLEQTQ YSWERQAAFR FKRKLPKYLL FTSPQENPWG HKRSYRLQIH SMADQVLPPG WQEEQAITWA RYPLAVTKYR ESELCSSSIY HQNDPWDPPV VFEQFLHNNE NIENEDLVAW VTVGFLHIPH SEDIPNTATP GNSVGFLLRP FNFFPEDPSL ASRDTVIVWP RDNGPNYVQR WIPEDRDCSM PPPFSYNGTY RPV (400-751 aa encoded by BC014093)
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amiloride binding protein 1 (amine oxidase (copper-containing)); Amiloride-binding protein; Amiloride-binding protein 1; amiloride-sensitive amine oxidase; Amine oxidase copper domain-containing protein 1; Diamine oxidase; Diamine oxidase [copper-containing]; Histaminase; KAO; Kidney amine oxidase
Gene Aliases: ABP; ABP1; AOC1; DAO; DAO1; KAO
UniProt ID: (Human) Q56II4
Entrez Gene ID: (Human) 26
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