This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Protein Aliases: ABP; Amiloride binding protein; amiloride binding protein 1 (amine oxidase (copper-containing)); amiloride binding protein 1 (amine oxidase, copper-containing); Amiloride-binding protein 1; amiloride-sensitive amine oxidase; Amiloride-sensitive amine oxidase [copper-containing]; Amine oxidase copper domain-containing protein 1; AOC1; DAO; DAO1; Diamine oxidase; Histaminase; KAO; Kidney amine oxidase
Gene Aliases: 1600012D06Rik; ABP; ABP1; AOC1; DAO; DAO1; KAO
UniProt ID: (Human) P19801