This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: ITKSKSEANL IPSQEPFPAS DNSGETPQRN GEGHTLPKTP SQAEPASHKG PKDAGRRRNS LPPSHQKPPR NPLSSSDAAP SPELQANGTG TQGLEATDTN GLSSSARPQG QQAGSPSKED KKQANIKRQL MTNFILGSFD DYSS
Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 57%.
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1 (By similarity).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACC-beta; Acetyl-CoA carboxylase 2; acetyl-Coenzyme A carboxylase beta; Biotin carboxylase
Gene Aliases: ACACB; ACC2; ACCB; HACC275
UniProt ID: (Human) O00763
Entrez Gene ID: (Human) 32
Molecular Function: ligase