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Product Details
17442-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACADL Fusion Protein Ag11530 (33-430 aa encoded by BC039063)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EERLETPSA KKLTDIGIRR IFSPEHDIFR KSVRKFFQEE VIPHHSEWEK AGEVSREVWE KAGKQGLLGV NIAEHLGGIG GDLYSAAIVW EEQAYSNCSG PGFSIHSGIV MSYITNHGSE EQIKHFIPQM TAGKCIGAIA MTEPGAGSDL QGIKTNAKKD GSDWILNGSK VFISNGSLSD VVIVVAVTNH EAPSPAHGIS LFLVENGMKG FIKGRKLHKM GLKAQDTAEL FFEDIRLPAS ALLGEENKGF YYIMKELPQE RLLIADVAIS ASEFMFEETR NYVKQRKAFG KTVAHLQTVQ HKLAELKTHI CVTRAFVDNC LQLHEAKRLD SATACMAKYW ASELQNSVAY DCVQLHGGWG YMWEYPIAKA YVDARVQPIY GGTNEIMKEL IAREIVFDK (33-430 aa encoded by BC039063)
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD; LCAD long chain acyl-CoA dehydrogenase; long-chain acyl-CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial
Gene Aliases: AA960361; ACAD4; ACADL; ACOADA; AU018452; C79855; LCAD
UniProt ID: (Human) P28330, (Mouse) P51174, (Rat) P15650
Entrez Gene ID: (Human) 33, (Mouse) 11363, (Rat) 25287
fatty-acyl-CoA binding
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
electron carrier activity
palmitoyl-CoA oxidase activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
temperature homeostasis
fatty acid beta-oxidation
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
cellular lipid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
protein homotetramerization
lipid homeostasis
oxidation-reduction process
regulation of cholesterol metabolic process
lipid metabolic process
fatty acid metabolic process
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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