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Invitrogen
ACADM Polyclonal Antibody
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Product Details
PA5-27200
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human ACADM. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Amount
74 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, Raji.
Predicted reactivity: Mouse (81%), Pig (83%), Chimpanzee (98%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; FLJ18227; FLJ93013; FLJ99884; MCAD; MCADH; Medium chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase (EC 1.3.99.3); Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; RP4-682C21.1; testicular tissue protein Li 7; unnamed protein product
Gene Aliases: ACAD1; ACADM; AU018656; MCAD; MCADH
UniProt ID: (Human) P11310, (Mouse) P45952
Entrez Gene ID: (Human) 34, (Mouse) 11364
liver development
glycogen biosynthetic process
organic acid metabolic process
regulation of gluconeogenesis
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
heart development
response to cold
carnitine metabolic process
post-embryonic development
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
response to starvation
carnitine biosynthetic process
medium-chain fatty acid metabolic process
medium-chain fatty acid catabolic process
cardiac muscle cell differentiation
metabolic process
protein homotetramerization
oxidation-reduction process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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