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Invitrogen
ACADM Polyclonal Antibody
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FIGURE: 1 / 5
ACADM Antibody (PA5-27201) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of ACADM was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: ACADM Polyclonal Antibody (Product # PA5-27201) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker. Blue: Hoechst 33342 staining.
Product Details
PA5-27201
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ACADM. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: Molt-4, Neuro2A, GL261, C8D30, PC-12.
Predicted reactivity: Mouse (89%), Rat (88%), Zebrafish (87%), Xenopus laevis (87%), Pig (91%), Chimpanzee (99%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acyl-CoA dehydrogenase C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain; acyl-Coenzyme A dehydrogenase, medium chain; FLJ18227; FLJ93013; FLJ99884; MCAD; MCADH; Medium chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase; Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; RP4-682C21.1; testicular tissue protein Li 7
Gene Aliases: ACAD1; ACADM; AU018656; MCAD; MCADH
UniProt ID: (Human) P11310, (Mouse) P45952, (Rat) P08503
Entrez Gene ID: (Human) 34, (Mouse) 11364, (Rat) 24158
fatty-acyl-CoA binding
acyl-CoA dehydrogenase activity
electron carrier activity
identical protein binding
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
medium-chain-acyl-CoA dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
isomerase activity
dehydrogenase
fatty acid beta-oxidation
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine biosynthetic process
medium-chain fatty acid metabolic process
medium-chain fatty acid catabolic process
lipid homeostasis
oxidation-reduction process
liver development
glycogen biosynthetic process
organic acid metabolic process
regulation of gluconeogenesis
lipid metabolic process
fatty acid metabolic process
heart development
metabolic process
response to cold
carnitine metabolic process
post-embryonic development
response to starvation
protein homotetramerization
cardiac muscle cell differentiation
response to nutrient
response to hormone
response to drug
response to copper ion
response to glucocorticoid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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