Sequence of this protein is as follows: AAALAGTMRG IIAKAVDHAT NRTQFGEKIH NFGLIQEKLA RMVMLQYVTE SMAYMVSANM DQGATDFQIE AAISKIFGSE AAWKVTDECI
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: acyl-Coenzyme A dehydrogenase, very long chain; Very long-chain specific acyl-CoA dehydrogenase, mitochondrial; VLCAD
Gene Aliases: ACAD6; ACADVL; LCACD; VLCAD
UniProt ID: (Human) P49748
Entrez Gene ID: (Human) 37