This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACE; ACE1; Angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; CD143; DCP; DCP1; Dipeptidyl carboxypeptidase I; dipeptidyl peptidase; Kininase II; MGC26566; MVCD3
Gene Aliases: Ace; AW208573; CD143; Dcp1
UniProt ID: (Mouse) P09470
Entrez Gene ID: (Mouse) 11421