The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
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Protein Aliases: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; ASAH3L; cancer related gene-liver 1 (CRG-L1); Cancer-related gene liver 1 protein; ceramide hydrolase; CRG-L1; haCER2; N-acylsphingosine amidohydrolase 3-like
Gene Aliases: 2410116I05Rik; ACER2; ALKCDase2; ASAH3L; CRG-L1; maCER2; PP11646
Molecular Function: hydrolase