This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
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Protein Aliases: Acyl-CoA thioester hydrolase 11; Acyl-CoA thioesterase 11; Acyl-coenzyme A thioesterase 11; Adipose-associated thioesterase; BFIT; Brown fat-inducible thioesterase; Palmitoyl-coenzyme A thioesterase; StAR-related lipid transfer (START) domain containing 14; START domain containing 14; thioeste; thioesterase superfamily member 1; thioesterase, adipose associated
Gene Aliases: 1110020M10Rik; 2010309H15Rik; ACOT11; AW060409; BFIT; BFIT1; KIAA0707; mKIAA0707; STARD14; THEA; THEM1