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Invitrogen
ACOT11 Polyclonal Antibody
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Product Details
PA5-103564
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ACOT11(Accession Q8WXI4), corresponding to amino acid residues V249-G299.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ACOT11.
Target Information
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acyl-CoA thioester hydrolase 11; Acyl-CoA thioesterase 11; Acyl-coenzyme A thioesterase 11; Adipose-associated thioesterase; BFIT; BFIT1; acyl-CoA thioesterase; acyl-CoA hydrolase; BFIT2; acyl-CoA thioesterase; acyl-CoA hydrolase; Brown fat-inducible thioesterase; Palmitoyl-coenzyme A thioesterase; StAR-related lipid transfer (START) domain containing 14; START domain containing 14; thioeste; thioesterase superfamily member 1; thioesterase, adipose associated; unnamed protein product
Gene Aliases: 1110020M10Rik; 2010309H15Rik; ACOT11; AW060409; BFIT; BFIT1; KIAA0707; mKIAA0707; STARD14; THEA; THEM1
UniProt ID: (Human) Q8WXI4, (Mouse) Q8VHQ9
Entrez Gene ID: (Human) 26027, (Rat) 100363074, (Mouse) 329910
protein binding
lipid binding
hydrolase activity
thiolester hydrolase activity
acyl-CoA hydrolase activity
carboxylic ester hydrolase activity
long-chain acyl-CoA hydrolase activity
CoA hydrolase activity
2-oxoglutaryl-CoA thioesterase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity
3-isopropylbut-3-enoyl-CoA thioesterase activity
glutaryl-CoA hydrolase activity
esterase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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