|Flow Cytometry (Flow)||1:10-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 549-575 amino acids from the C-terminal region of human ACOT11|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acyl-CoA thioester hydrolase 11; Acyl-CoA thioesterase 11; Acyl-coenzyme A thioesterase 11; Adipose-associated thioesterase; BFIT; Brown fat-inducible thioesterase; StAR-related lipid transfer (START) domain containing 14; STARD14; START domain containing 14; THEA; THEM1; thioeste; thioesterase superfamily member 1; thioesterase, adipose associated
Gene Aliases: ACOT11; BFIT; KIAA0707; STARD14; THEA; THEM1
UniProt ID: (Human) Q8WXI4
Entrez Gene ID: (Human) 26027
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