Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (PubMed:16940157). ACOT4 is a peroxisomal succinyl-coenzyme A thioesterase can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs (PubMed:16940157). [UniProt]
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Protein Aliases: Acyl-CoA thioesterase 4; Acyl-coenzyme A thioesterase 4; Peroxisomal acyl coenzyme A thioester hydrolase Ib; peroxisomal acyl-CoA thioesterase 2B; Peroxisomal long-chain acyl-CoA thioesterase Ib; Peroxisomal succinyl-coenzyme A thioesterase; PTE-2b; PTE-Ib
Gene Aliases: ACOT4; B430212I04Rik; PTE-Ib; PTE1B; PTE2B; PTEIB