Sequence of this protein is as follows: LTQGPQNPKK QGIFHIHEVR DKLREIVGAS TNWRDHVKAM EERKLLHSFL AKSQDGLPPR RMKDSYIEVL LPLGSEPELR EKYLTVQNTV RFGRILEDLD SLGVLICYMH NKIHSAKMSP LSIVTALVDK IDMCKKSLSP EQDIKFSGHV SWVGKTSMEV KMQMFQLHGD EFCPVLDATF VMVARDSENK GPAFVNPLIP ESPEEEELFR QGELNKGRRI AFSSTSLLK
Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT9 (acyl-CoA thioesterase 9), also known as ACATE2, MT-ACT48 (mitochondrial acyl-CoA thioesterase of 48 kDa) or CGI-16, is a 406 amino acid member of the acyl-CoA hydrolase protein family. ACOT9 contains a C-terminal 80-amino acid domain that is conserved from mouse to human, suggesting that the C-terminus may confer the catalytic activity of ACOT9. The gene encoding ACOT9 is located on chromosome X and the expressed ACOT9 protein is localized to the mitochondrion.
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Protein Aliases: Acyl coenzyme A thioester hydrolase 2; Acyl-CoA thioester hydrolase 9; Acyl-CoA thioesterase 9; acyl-Coenzyme A thioesterase 2, mitochondrial; Acyl-coenzyme A thioesterase 9, mitochondrial; Mitochondrial 48 kDa acyl-CoA thioester hydrolase 1; mitochondrial Acyl-CoA Thioesterase; Mt-ACT48.1; MTE-2; p48; Protein U8
Gene Aliases: 0610041P13Rik; ACATE2; ACOT9; C76421; CGI-16; MT-ACT48; MTACT48; p48; U8