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Alomone Labs, LTD
CCR9 (extracellular) Polyclonal Antibody
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FIGURE: 1 / 2
CCR9 (extracellular) Antibody (ACR-029-25UL) in WB
Western blot analysis of human acute T cell leukemia (Jurkat) (lanes 1 and 3), human melanoma (MALME-3M) (lanes 2 and 4), human adenocarcinoma (HT-29) (lanes 5 and 7) and mouse T-cell lymphoma (TK-1) (lanes 6 and 8) cell line lysates: - 1,2,5,6. Anti-CCR9 (extracellular) Antibody (#ACR-029), (1:200).3,4,7,8. Anti-CCR9 (extracellular) Antibody , preincubated with CCR9 (extracellular) Blocking Peptide (#BLP-C... View More
Product Details
ACR-029-25UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)DESTKLKSAVLTLK, corresponding to amino acid residues 205-218 of human CCR9, 2nd extracellular loop
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR-9; CCR9A; CCR9B; CDw199; CDw199 antigen; chemokine (C-C motif) receptor 9; Chemokine C-C receptor 10; G protein-coupled receptor; G protein-coupled receptor 28; G-protein coupled receptor 28; GPR-9-6; unnamed protein product
Gene Aliases: A130091K22Rik; CC-CKR-9; CCR9; CDw199; Cmkbr10; GPR-9-6; GPR28
UniProt ID: (Human) P51686, (Mouse) Q9WUT7
Entrez Gene ID: (Human) 10803, (Rat) 282832, (Mouse) 12769
chemotaxis
immune response
G-protein coupled receptor signaling pathway
chemokine-mediated signaling pathway
signal transduction
CD8-positive, gamma-delta intraepithelial T cell differentiation
cellular defense response
positive regulation of cytosolic calcium ion concentration
calcium-mediated signaling
cell chemotaxis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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