Immunogen sequence: HHLPQFDTKV IIQTLLKYPI NHFWGVSSIY RMILQQDFTS IRFPALEHCY TGGEVVLPKD QEEWKRRTG
Highest antigen sequence identity to the following orthologs: Mouse - 58%, Rat - 57%.
ACSM1 has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). This protein acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro). This protein functions as GTP-dependent lipoate-activating enzyme that generates the substrate for lipoyltransferase.
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Protein Aliases: Acyl-CoA synthetase medium-chain family member 1; Acyl-coenzyme A synthetase ACSM1, mitochondrial; Benzoate--CoA ligase; Butyrate CoA ligase; Butyrate--CoA ligase 1; butyryl Coenzyme A synthetase 1; Butyryl-coenzyme A synthetase 1; Lipoate-activating enzyme; medium-chain acyl-CoA synthetase; Middle-chain acyl-CoA synthetase 1; Xenobiotic/medium-chain fatty acid-CoA ligase HXM-B
Gene Aliases: ACSM1; BUCS1; LAE; MACS1
UniProt ID: (Human) Q08AH1
Entrez Gene ID: (Human) 116285