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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ACSS2 Antibodies

          Invitrogen

          ACSS2 Polyclonal Antibody

          2 Published Figures
          3 References
          View all (38) ACSS2 antibodies

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          Cite ACSS2 Polyclonal Antibody

          • Antibody Testing Data (6)
          • Published Figures (2)
          ACSS2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ACSS2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          ACSS2 Antibody (PA5-52059) in ICC/IF

          Immunofluorecent analysis of ACSS2 in human cell line A-431 using ACSS2 Polyclonal Antibody (Product # PA5-52059). Staining shows localization to nucleoplasm, cytosol and vesicles. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          ACSS2 Antibody in Immunocytochemistry (ICC/IF)
          ACSS2 Antibody in Immunohistochemistry (IHC)
          ACSS2 Antibody in Immunohistochemistry (IHC)
          ACSS2 Antibody in Immunohistochemistry (IHC)
          ACSS2 Antibody in Immunohistochemistry (IHC)
          ACSS2 Antibody in Western Blot (WB)
          ACSS2 Antibody in Immunohistochemistry (IHC)
          ACSS2 Antibody in Western Blot (WB)
          ACSS2 Polyclonal Antibody

          Product Details

          PA5-52059

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          Affinity Purification (AP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          C. elegans

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ACSS2. Recombinant protein control fragment (Product #RP-102332).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2637634

          Product Specific Information

          Immunogen sequence: PGETTQITYH QLLVQVCQFS NVLRKQGIQK GDRVAIYMPM IPELVVAMLA CARIGALHSI VFAGFSSESL CERILDSSCS LLITTDAFYR GEKLVNLKEL ADEALQKCQE KGFPVRCCIV VKHLGRAELG MGDSTSQSPP IKRSCPDVQ

          Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

          Target Information

          This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: AceCS1; acetate thiokinase; Acetate--CoA ligase; acetate-CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 2 (ADP forming); Acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; Propionate--CoA ligase

          View more View less

          Gene Aliases: ACAS2; ACECS; ACS; ACSA; ACSS2; dJ1161H23.1

          View more View less

          UniProt ID: (Human) Q9NR19

          View more View less

          Entrez Gene ID: (Human) 55902

          View more View less

          Function(s)
          acetate-CoA ligase activity ATP binding AMP binding ligase
          Process(es)
          ethanol oxidation lipid biosynthetic process acetate biosynthetic process acetyl-CoA biosynthetic process from acetate propionate biosynthetic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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