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Invitrogen
ACTR3B Polyclonal Antibody
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FIGURE: 1 / 1
ACTR3B Antibody (PA5-96824) in WB
Western blot analysis of ACTR3B in extracts of various cell lines. Samples were incubated with ACTR3B Polyclonal antibody (Product # PA5-96824) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-96824
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 189-418 of human ACTR3B (NP_0651781)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Amount
38 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CIKHIPIAGR DITYFIQQLL REREVGIPPE QSLETAKAIK EKYCYICPDI VKEFAKYDVD PRKWIKQYTG INAINQKKFV IDVGYERFLG PEIFFHPEFA NPDFMESISD VVDEVIQNCP IDVRRPLYKN VVLSGGSTMF RDFGRRLQRD LKRVVDARLR LSEELSGGRI KPKPVEVQVV THHMQRYAVW FGGSMLASTP EFFQVCHTKK DYEEYGPSIC RHNPVFGVMS; Positive Samples: HeLa, NCI-H125, Mouse brain; Cellular Location: Cell projection, Cytoplasm, cytoskeleton
Target Information
ACTR3B plays a role in the organization of the actin cytoskeleton.ACTR3B may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ACTR3B may decrease the metastatic potential of tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 3B; actin-related protein 3-beta; Actin-related protein 3B; actin-related protein Arp11; Actin-related protein ARP4; ARP3 actin related protein 3 homolog B; ARP3 actin-related protein 3 homolog B; ARP3-beta; DKFZp686O24114; unnamed protein product
Gene Aliases: 9630005C02; ACTR3B; ARP11; Arp3b; ARP3BETA; ARP4; AW047569
UniProt ID: (Human) Q9P1U1, (Mouse) Q641P0
Entrez Gene ID: (Human) 57180, (Mouse) 242894
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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