ACTR3B plays a role in the organization of the actin cytoskeleton.ACTR3B may function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. ACTR3B may decrease the metastatic potential of tumors.
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Protein Aliases: Actin-like protein 3B; actin-related protein 3-beta; Actin-related protein 3B; actin-related protein Arp11; Actin-related protein ARP4; ARP3 actin-related protein 3 homolog B; ARP3-beta
Gene Aliases: ACTR3B; ARP11; ARP3BETA; ARP4
UniProt ID: (Human) Q9P1U1
Entrez Gene ID: (Human) 57180