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Fabgennix

ADA Polyclonal Antibody

View all (30) ADA antibodies

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ADA Polyclonal Antibody

Product Details

ADA-101AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 50-100 on human Adenosine Deaminase / Adenosine Aminohydrolase.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5

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Gene Aliases: ADA; ADA1

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UniProt ID: (Human) P00813, (Mouse) P03958, (Rat) Q920P6

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Entrez Gene ID: (Human) 100, (Mouse) 11486, (Rat) 24165

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Function(s)
adenosine deaminase activity protein binding zinc ion binding hydrolase activity deaminase activity metal ion binding 2'-deoxyadenosine deaminase activity purine nucleoside binding deaminase
Process(es)
allantoin metabolic process response to hypoxia in utero embryonic development trophectodermal cell differentiation liver development placenta development germinal center B cell differentiation germinal center formation positive regulation of germinal center formation negative regulation of leukocyte migration mature B cell apoptotic process negative regulation of mature B cell apoptotic process adenosine catabolic process deoxyadenosine catabolic process AMP catabolic process xenobiotic metabolic process apoptotic process smooth muscle contraction cell adhesion nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process positive regulation of heart rate response to purine-containing compound calcium-mediated signaling T cell differentiation lung development positive regulation of B cell proliferation purine nucleotide salvage GMP salvage T cell differentiation in thymus positive regulation of T cell differentiation in thymus regulation of cell-cell adhesion mediated by integrin B cell proliferation T cell activation negative regulation of apoptotic process penile erection purine-containing compound salvage hypoxanthine salvage cellular amide catabolic process AMP salvage regulation of circadian sleep/wake cycle, sleep regulation of T cell differentiation positive regulation of T cell differentiation positive regulation of smooth muscle contraction dAMP catabolic process dATP catabolic process adenosine metabolic process hypoxanthine biosynthetic process inosine biosynthetic process xanthine biosynthetic process alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation lung alveolus development Peyer's patch development embryonic digestive tract development negative regulation of inflammatory response positive regulation of calcium-mediated signaling T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of T cell activation leukocyte migration negative regulation of adenosine receptor signaling pathway negative regulation of penile erection thymocyte apoptotic process negative regulation of thymocyte apoptotic process mucus secretion negative regulation of mucus secretion histamine secretion response to vitamin E negative regulation of circadian sleep/wake cycle, non-REM sleep response to morphine aging response to drug response to hydrogen peroxide
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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