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Proteintech
ADAM12 Polyclonal Antibody
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Product Details
14139-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADAM12 Fusion Protein Ag5206 (31-350 aa encoded by BC060804)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody can recognize all isoforms of ADAM12. ADAM12 has 4 forms: 120 kDa full-length form, 90 kDa mature (processed form that lack the pro domain);50-68 kDa degradation product and 27 kDa pro domain.
Immunogen sequence: VSLWNQGRA DEVVSASVRS GDLWIPVKSF DSKNHPEVLN IRLQRESKEL IINLERNEGL IASSFTETHY LQDGTDVSLA RNYTGHCYYH GHVRGYSDSA VSLSTCSGLR GLIVFENESY VLEPMKSATN RYKLFPAKKL KSVRGSCGSH HNTPNLAAKN VFPPPSQTWA RRHKRETLKA TKYVELVIVA DNREFQRQGK DLEKVKQRLI EIANHVDKFY RPLNIRIVLV GVEVWNDMDK CSVSQDPFTS LHEFLDWRKM KLLPRKSHDN AQLVSGVYFQ GTTIGMAPIM SMCTADQSGG IVMDHSDNPL GAAVTLAHEL G (31-350 aa encoded by BC060804)
Target Information
ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM; ADAM 12; ADAMs; Disintegrin and metalloproteinase domain-containing protein 12; meltrin alpha; Meltrin-alpha; metalloendopeptidases; metalloprotease-disintegrin 12 transmembrane; PRO545; RP11-295J3.5; UNQ346
Gene Aliases: ADAM12; ADAM12-OT1; CAR10; MCMP; MCMPMltna; mKIAA4001; MLTN; MLTNA; UNQ346/PRO545
UniProt ID: (Human) O43184, (Mouse) Q61824
Entrez Gene ID: (Human) 8038, (Mouse) 11489
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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