ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
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Protein Aliases: a disintegrin and metallopeptidase domain 9 (meltrin gamma); a disintegrin and metalloprotease domain 9; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 9 (meltrin gamma); ADAM; ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); adam9; ADAMs; Cellular disintegrin-related protein; cone rod dystrophy 9; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; meltrin gamma; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
Gene Aliases: ADAM9; AU020942; CORD9; KIAA0021; MCMP; MDC9; mKIAA0021; MLTNG
Molecular Function: metalloprotease