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Invitrogen
ADAM9 Polyclonal Antibody
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FIGURE: 1 / 6
ADAM9 Antibody (PA5-25959) in IHC (P)
Immunohistochemistry analysis of ADAM9 in formalin-fixed and paraffin-embedded human lung carcinoma. Samples were incubated with ADAM9 polyclonal antibody (Product # PA5-25959) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Details
PA5-25959
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 704-733 amino acids from the C-terminal region of human ADAM9
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); ADAMs; Cellular disintegrin-related protein; cone rod dystrophy 9; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
Gene Aliases: ADAM9; CORD9; KIAA0021; MCMP; MDC9; MLTNG
UniProt ID: (Human) Q13443
Entrez Gene ID: (Human) 8754
activation of MAPKK activity
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
response to manganese ion
cell migration
keratinocyte differentiation
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
monocyte activation
response to hydrogen peroxide
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
PMA-inducible membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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