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Proteintech
ADAMTS1 Polyclonal Antibody
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Product Details
12749-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADAMTS1 Fusion Protein Ag3485 (253-546 aa encoded by BC036515)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FVSSHRYVE TMLVADQSMA EFHGSGLKHY LLTLFSVAAR LYKHPSIRNS VSLVVVKILV IHDEQKGPEV TSNAALTLRN FCNWQKQHNP PSDRDAEHYD TAILFTRQDL CGSQTCDTLG MADVGTVCDP SRSCSVIEDD GLQAAFTTAH ELGHVFNMPH DDAKQCASLN GVNQDSHMMA SMLSNLDHSQ PWSPCSAYMI TSFLDNGHGE CLMDKPQNPI QLPGDLPGTS YDANRQCQFT FGEDSKHCPD AASTCSTLWC TGTSGGVLVC QTKHFPWADG TSCGEGKWCI NGKCV (253-546 aa encoded by BC036515)
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1); a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; ADAMTS1; extracellular protein with metalloprotease and TSP domains; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; metalloprotease and thrombospondin-1; METH-1; unnamed protein product
Gene Aliases: ADAM-TS1; ADAMTS; ADAMTS-1; ADAMTS1; C3-C5; KIAA1346; METH-1; METH1
UniProt ID: (Human) Q9UHI8, (Mouse) E9QMN9
Entrez Gene ID: (Human) 9510, (Mouse) 11504, (Rat) 79252
ovulation from ovarian follicle
kidney development
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
negative regulation of angiogenesis
extracellular matrix organization
heart trabecula formation
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
positive regulation of neuron projection development
ovulation
tooth eruption
cellular response to vitamin D
cellular response to parathyroid hormone stimulus
cellular response to prostaglandin E stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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